Chicheley Brook – formerly known by the alternative name Tickford Brook – is a 14.11 km (8.77 mi) long river in Buckinghamshire, England, that is a tributary to the River Great Ouse. Located entirely in the City of Milton Keynes, the river rises near the village of Cranfield, flows north-west around North Crawley then turns west before Hardmead; it then follows a southerly course past Chicheley for 1.90 km (1.18 mi) before resuming its westerly course and flowing into the River Great Ouse near Newport Pagnell.